Endocrine Abstracts

Introduction: PCSK9 inhibitors (iPCSK9) have previously been evaluated through controlled clinical trials showing up to 60% reduction in LDL cholesterol concentrations. However, we still do not have enough data regarding the real life experience of the treatment.Objectives: 1) Describe patients with hypercholesterolemia treated with iPCSK9 in clinical practice.2) Evaluate treatment efficacy and safety.Methods...

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves’ disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

Introduction: The role of external beam radiotherapy (EBRT) as primary or as adjuvant therapy in the non-undifferentiated thyroid cancer (NUTC) is controversial. Most published data refer to retrospective case series. Therefore, little is known about the correlation between tumor markers and radiologic measurements of tumor response.Objectives: The study aimed to analyze the kinetics of tumor markers and radiologic measurement of tumor response after EBR...